Drugs & Vitamins

Pamidronate Injection Active Ingredients: Pamidronate Injection Representative Names: Aredia What is pamidronate injection? What should I tell my health care provider before I take this medicine? How should I use this medicine? What if I miss a dose? What drug(s) may interact with pamidronate? What side effects may I notice from receiving pamidronate? What should I watch for while taking pamidronate? Where can I keep my medicine? What is pamidronate injection? (Back to top) PAMIDRONATE (Aredia®) lowers the amount of calcium in your blood. High blood calcium levels can make you confused and tired, and cause stomach pain and muscle weakness. Pamidronate, by lowering calcium levels in the blood, help relieve these symptoms. Generic pamidronate injection is available. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •aspirin-sensitive asthma •dental disease •kidney disease •an unusual or allergic reaction to pamidronate, other medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should I use this medicine? (Back to top) Pamidronate is for injection or infusion into a vein. It is usually given by a healthcare professional in a hospital or clinic setting. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. What if I miss a dose? (Back to top) This does not apply. What drug(s) may interact with pamidronate? (Back to top) •antiinflammatory drugs (NSAIDs, such as ibuprofen and naproxen) •certain antibiotics given by injection •certain water pills or diuretics (examples include Bumex®, Demadex®, Lasix®, or furosemide) •cyclosporine •parathyroid hormone •tacrolimus •teriparatide Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from receiving pamidronate? (Back to top) Side effects that you should report to your prescriber or health care professional as soon as possible: •blood in your stool •constant jaw pain, especially burning or cramping •eye inflammation, pain, or vision change •increase in blood pressure •muscle cramps or weakness •very stiff muscles, unable to move easily Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •bone pain •constipation •fever •joint pain •loss of appetite •muscle pain •nausea, vomiting •pain or difficulty passing urine •redness, pain, swelling, or irritation at the injection site •tiredness •upset stomach What should I watch for while taking pamidronate? (Back to top) If you get black, tarry stools or vomit up what look like coffee grounds, call your prescriber or health care professional at once. You may have a bleeding ulcer. Visit your prescriber or health care professional for regular checks on your progress. Your prescriber or health care professional may schedule blood tests to make sure you do not have unwanted side effects. It may take 7 days before seeing the full benefits of this medicine. Where can I keep my medicine? (Back to top) This medication is usually only given in a hospital or clinic. You will not keep this medicine at home. Last Updated:10/12/2005 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.